Screenings & Tests

What Is an HPV Test? Who Needs One and What Results Mean

What an HPV test checks for, how it differs from a Pap smear, who should get one and how often, self-collection options and what positive results mean.

Gloved hands holding a sealed swab test kit in a bright, calm clinic
Illustration: US Gynecologists / AI-generated.

Key takeaways

  • An HPV test looks for high-risk types of human papillomavirus, the cause of nearly all cervical cancers.
  • From age 30, the USPSTF lists an HPV test every five years as a screening option, and its 2024 draft update makes it the preferred one.
  • A positive result is common and does not mean cancer; it means you need follow-up.
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An HPV test is one of the most effective cancer screening tools we have. It doesn’t look for cancer. It looks for the virus that causes almost all cervical cancers, years before any cell changes could become dangerous.

What is HPV?

Human papillomavirus (HPV) is extremely common: most sexually active people get it at some point. Most infections cause no symptoms and clear on their own within a year or two. A few high-risk types, especially HPV 16 and 18, can persist and slowly cause changes in cervical cells. Over many years, some of those changes can turn into cancer if they aren’t found and treated.

What the test looks for

An HPV test checks a sample of cells from your cervix or vagina for high-risk HPV types. Some tests also report whether HPV 16 or 18 specifically is present, which helps decide next steps. It isn’t a test for genital warts, which are caused by low-risk types, and it doesn’t screen for other infections.

HPV test vs Pap test

HPV testPap test (cytology)
Looks forHigh-risk HPV virusAbnormal cervical cells
Main useScreening from 30 (25 in ACS guidance)Screening from 21 to 29, or an alternative after 30
Usual interval if normalEvery 5 yearsEvery 3 years
SampleCervical swab, or vaginal self-collectionCervical swab

Co-testing means doing both tests on the same sample, every five years. Our guide to Pap smear guidelines by age covers the full schedule.

Who should get one, and how often?

Under the US Preventive Services Task Force’s 2018 recommendation, people with a cervix aged 30 to 65 can choose an HPV test every five years, co-testing every five years or a Pap test every three years. In late 2024, the USPSTF published a draft update that would make HPV testing every five years the preferred option from age 30 and include self-collected samples; as of September 2026, it has not been finalised. The American Cancer Society recommends starting primary HPV testing at 25.

HPV tests aren’t used for routine screening in younger people, because infections are so common in the teens and twenties and usually clear without treatment.

Self-collection

You may be able to collect your own sample with a vaginal swab, either at a clinic or, with FDA-approved kits, at home. The American Cancer Society’s December 2025 update accepts self-collected samples from 25 to 65, though it still prefers a sample taken by a clinician. Studies show self-collected samples are about as accurate as clinician-collected ones for detecting precancer. Current consensus guidance suggests repeating a negative self-collected test after three years rather than five. Ask your clinician whether it’s an option for you; people at higher risk may still need a clinician-collected sample.

What your results mean

  • Negative: no high-risk HPV was found. Your next screening is usually due in five years, or three after a self-collected test.
  • Positive: high-risk HPV was found. This is common and doesn’t mean you have cancer. Depending on the HPV type, your Pap result and your history, the next step may be repeat testing in a year or a closer look with colposcopy. Our guide to abnormal Pap smear results explains the follow-up.

Getting ready for the test

For two days beforehand, it’s usually best to avoid douching, vaginal medicines or products and sex, unless your clinic says otherwise. Tell your clinician if you’ve found past exams uncomfortable; our guide to your first gynecologist visit has tips for feeling in control.

HPV vaccination

The CDC recommends HPV vaccination at ages 11 to 12 (it can start at 9), with catch-up vaccination through age 26. Some adults aged 27 to 45 may benefit after talking with their clinician. Vaccinated people still need regular screening.

Frequently asked questions

Does a positive HPV test mean my partner was unfaithful?

No. HPV can stay undetectable for years before showing up on a test, so a positive result can’t tell you when or from whom the infection came.

Can men get an HPV test?

There’s no approved routine HPV screening test for men. Vaccination is the main prevention for everyone.

Is HPV testing covered by insurance?

Cervical cancer screening is a preventive service most plans must cover without cost-sharing. Our insurance guide explains the details.

Sources

  1. USPSTF — Cervical cancer screening (2024 draft update)
  2. American Cancer Society — Cervical cancer screening guidelines (updated December 2025)
  3. CDC — About HPV

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